Migraine attacks occur when arteries to the brain become narrow (constrict) and then widen (dilate) which activates nearby pain receptors. What causes the blood vessels to do this is not known but abnormally low blood levels of a chemical substance called serotonin, which is involved in nerve cell communication (neurotransmitter), may trigger the contractions.
Migraine trigger factors include:
- stress
- hormonal changes (particularly in relation to the menstrual cycle or the use of oral contraceptives)
- physical exertion
- too little sleep
- skipping meals
- foods such as alcohol, fatty foods and tea or coffee
Migraine headache, which is typically throbbing, unilateral and aggravated by activity, is the most prominent feature of a migraine attack. Other symptoms include photophobia (sensitivity to light), phonophobia (sensitivity to sound), visual disturbances, nausea and or vomiting.
Where sufferers experience aura, it nearly always precedes the headache, lasts between 5 and 60 minutes and usually includes visual symptoms such as flashing lights or a growing black spot surrounded by shimmering lights.
Migraine attacks vary in frequency. The average is about one attack per month, but 10% of sufferers experience more than one attack every week and women generally experience more attacks than men.
Diagnosis is based entirely upon symptoms as the causes of migraine are unclear and there are no diagnostic tests. Doctors must take a careful history from their patients. Diary cards – used to record information about specific symptoms – can be useful to distinguish between different types of headache. Migraine is consistently under-diagnosed, partly because many sufferers do not consult a doctor.
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